3D Bioprinter Can Heal Wounds

Many of us who do not like the color of our skins secretly dreamt of gaining a new skin of our choice whenever we looked at our favorite celebrities or the people who had envious skin tones & complexions. Well!!! These are possible only in Utopia and let us get back to reality. We are trying to find ideal solutions to cure the wounds caused for various reasons and take longer than usual to heal fully.

As a result of multiple researches, scientists at Wake Forest Institute for Regenerative Medicine (WFIRM) scientists created a mobile skin bio-printing system—the first of its kind—that allows bi-layered skin to be printed directly into a wound.

“The exclusive aspect of this technology is the flexibility of the system and the ability to provide on-site management of extensive wounds by scanning and measuring them in order to deposit the cells directly where they are needed to create skin,” said Sean Murphy, Ph.D., a WFIRM assistant professor who was lead author of the paper published this month in Nature’s Scientific Reports journal.

Across the nation, many Americans suffer from wounds that refuse to heal as they are caused due to diabetes unless and until treated multiple times. Also, injuries caused due to fire accidents or wars, leave unforgettable scars on bodies and the task to cure them also is cumbersome.

A biopsy of unaffected tissues is done to separate the major skin cells—dermal fibroblasts and epidermal keratinocytes. Fibroblasts are cells that synthesize the extracellular matrix and collagen that play a critical role in wound healing while keratinocytes are the predominant cells found in the epidermis, the outermost layer of the skin.

The researchers demonstrated proof-of-concept of the system by printing skin directly onto pre-clinical models.

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